BoxGroup was founded in 2007 by David Tisch, grandson of Loews Corporation co-founder Laurence Tisch, and Adam Rothenberg, both of whom also built Techstars NYC into a cornerstone of the New York startup scene before leaving to focus on BoxGroup full-time in 2012. The firm's small early offices near Union Square became an informal co-working hub for its own portfolio companies, and that proximity produced its most famous bet: Zach Perret turned down a job offer at BoxGroup to found Plaid instead, and BoxGroup became the fintech company's first institutional investor. Comfortable investing on 'more vision than traction,' as Tisch describes it, BoxGroup has made more than 600 investments across fintech, enterprise software, consumer, and deep tech, with major exits including Flatiron Health (acquired by Roche for $1.9 billion), PillPack, Matterport, and Trello, and now manages $550 million across two new funds as of a 2025 raise marking the firm's 16th year.
Flatiron Health's $1.9 billion acquisition by Roche in 2018 - BoxGroup was an early investor in the healthcare data company, one of several major exits alongside PillPack, Matterport, and Trello