Cultivation Capital is a venture capital firm founded in St. Louis in 2012 that says it invests in young companies whose ideas have potential to transform the way we live and work. It writes initial cheques of $100k to $3.5M from Series Seed through Series B. Rather than one blended fund it runs five named investment strategies, each with its own fund family and its own partners: Life Sciences and Health Tech (therapeutics, diagnostics, research tools and reagents, medical devices and healthcare information technology); Software and IT (early-stage technology companies with product, revenue and traction); Agriculture and Food Tech (crops, animal health, precision agriculture, sustainability, logistics and food ingredients); Midwest Seed Stage (fintech, healthcare and agtech companies active in St. Louis or the greater Midwest); and Geospatial Tech (early-stage companies using location intelligence). It has also run a separate Fintech Fund. The firm operates from St. Louis with additional offices in Greenville, Philadelphia and Chicago.
2012
Cultivation Capital launches in St. Louis and holds its first investment committee meeting on 17 April 2012; Techli names Rick Holton Jr., Brian Matthews, Peter Esparrago and Jim McKelvey as general partners and Kyle Welborn and Israel Vicars as associate partners.
2012
Missouri Founders Technology Fund, LLC files a Form D from St. Louis on 25 July 2012 naming Brian Matthews, Peter Esparrage and Jim McKelvey as managers, with a first sale on 28 March 2012.
2013
Cultivation Capital Life Sciences Fund, LLC files its first Form D on 18 June 2013, opening the firm's life sciences fund family.
2015
Cultivation Capital Tech Fund II, LLC files its Form D on 28 January 2015.
2016
The firm opens two further fund families in the same year: Cultivation Capital Fintech Fund, L.P. (Form D filed 30 September 2016) and Cultivation Capital Life Sciences Fund II, LLC (Form D filed 1 November 2016).
2018
Cultivation Capital Tech Fund III, L.P. files its Form D on 24 August 2018.
2021
Cultivation Capital Geospatial Tech Fund I, L.P. begins selling on 7 May 2021 and reports $22,650,000 sold against a $50,000,000 offering in its amended Form D of 29 April 2022.
2021
Cultivation Twain Seed Fund II, L.P. files a Form D on 9 August 2021 naming Cultivation Capital, LLC as management company and Twain Financial Partners as sub management company, a jointly branded vehicle.
2022
Cultivation Capital Tech Fund IV, LP begins selling on 16 February 2022 and reports $54,750,000 sold against a $100,000,000 offering in its amended Form D of 19 April 2023.
2024
Cultivation Capital Seed Fund III, L.P. begins selling on 9 May 2024 and reports $14,030,500 sold in its amended Form D of 8 May 2025; Cultivation Capital AgTech Fund IV, L.P. begins selling on 26 June 2024 with a $20,000,000 offering, reported by Global AgInvesting on 17 July 2024.
2025
Cultivation Capital Life Sciences Fund IV, LP begins selling on 4 April 2025 against a $40,000,000 offering, reporting $6,500,000 sold in its amended Form D of 26 March 2026.