Big Brain Holdings describes itself on its own site as a 'Multi-Strategy Investment Firm' and as 'a global multi-stage investment firm backing funds and founders accelerating emerging frontiers in technology', adding 'Rooted in cypherpunk, we back conviction and visionaries pursuing radical ideas'. It says it invests in funds as well as directly in companies. Its four stated focus areas are Artificial Intelligence, Robotics, Decentralized Infra and Consumer & Deeptech, and its portfolio filter also carries Crypto, Advanced Compute and Data/AI Infra. The site states 120+ portfolio companies, 60+ funds invested, 8+ years active and 40+ countries. Boilerplate the firm supplied for a September 2024 portfolio company announcement described it as 'a Web3 fund with investments in Solana, The Graph, and Arweave', so the current AI and robotics framing is a broadening of an originally crypto-focused mandate.