Catalio Capital Management vs New Enterprise Associates

A side-by-side comparison of two Healthcare investors: Catalio Capital Management (Power Score 82/100) and New Enterprise Associates (Power Score 80/100), both ranked among the most active firms tracked in this category.

Catalio Capital ManagementNew Enterprise Associates
Power Score™ 82/100 80/100
Assets Managed $2B (the homepage prints "$2B In assets under management *as of 10/01/2025"; the raw date form is carried here because for a US filer 10/01/2025 reads as 1 October 2025) $25B+
Founded 2020 1977
Headquarters New York, NY Menlo Park, CA
Sectors Healthcare, Biotech, Medical Devices, Diagnostics, Life Sciences, Data Technology, Healthcare, Life Sciences

Catalio Capital Management

Catalio Capital Management is an SEC-registered investment adviser (CRD 310374, SEC file 801-121976) that describes itself as focused on the full lifecycle of innovative healthcare investing, across private, public and credit markets. It runs four stated strategies: Private Equity and Venture Capital, investing in privately held innovative healthcare companies at all stages from inception to IPO; Structured Opportunities, providing senior-secured financing to healthcare innovators; Public Equities, a fundamental equity long/short strategy investing in global healthcare equities across innovative drugs, devices, diagnostics and data; and Co-Investments offering limited partners direct access to selected deals. The firm operates from New York, Washington DC and London, and states that it works with a network of more than 45 Venture Partners who hold equity interests across all Catalio strategies. It is a multi-strategy healthcare investment manager rather than a pure venture partnership.

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New Enterprise Associates

NEA was founded in 1977 by three men who each brought a different piece of the puzzle: Dick Kramlich, who had trained under legendary investor Arthur Rock; Frank Bonsal, an investment banker who had taken startups public; and Chuck Newhall, who had managed investment funds at T. Rowe Price. Deliberately built with offices on both coasts from day one - unusual for the era - NEA's first fund raised just $16 million, a fraction of the more than $25 billion it manages today.

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